Advanced Diagnostic Research

Diagnostic research in the past focused particularly on estimating the sensitivity and specificity of individual diagnostic tests. This online medical course will demonstrate that this so called ‘test research’ is not necessarily the same as diagnostic research.

Dr. K. (Kevin). Jenniskens
Assistant Professor B, UMC Utrecht
Quick overview
  • 3 weeks - 14 hrs / wk
  • Academic Certificate
  • 1.5 EC
  • Online
  • English
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Enrollment closes 18/11/2024 176 days left to apply
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Course description

Learning objectives

At the end of this course, you’ll should be able to:

• Describe the principles and design of primary diagnostic studies
• Describe the advantages and disadvantages of different approaches in primary diagnostic studies
• Describe the validity aspects of primary diagnostic studies
• Describe the methods for data collection in the different study designs of primary diagnostic studies
• Explain the differences between different design and analytical approaches in primary diagnostic studies
• Name the different measures of diagnostic value or accuracy that can be calculated from primary diagnostic studies
• Explain and use modern design and analytical approaches instead of the classical approach in primary diagnostic studies
• Describe the clinical utility and health technology assessment of diagnostic impact studies
• Choose an appropriate study design and analytical approach to be used in a specific situation or to answer a specific study question in both primary diagnostic studies


The exams are, by default, online using online proctoring. If you wish to take the exam on-site in Utrecht, the Netherlands, this is possible as well.

Exam edition November 2023
The exam will take place on December 15th, 2023 from 14:15 – 17:15 CET. The re-examination will take place on February 2st, 2024 from 14:15 – 17:15 CET. Note: these times might be subject to change. The exact time and place will be announced as soon as possible in the learning environment and any changes announced there will overrule the information here.

Taking the exam is not compulsory. However, if you want to receive the Course Certificate and the credits, it is obligatory to take the exam. You are allowed to redo the exam once.

It might be that, due to a force majeure situation, you cannot be present during the first exam moment.

• MSc Epidemiology Postgraduate students must then, preferably prior to the first exam option, ask the academic counsellor for permission to be absent. Please note that the academic counsellor can ask for some form of proof of your absence (e.g. in case of illness) to establish if you are applicable for authorized absence. Jaco de Fockert-Koefoed, MSc is the academic counsellor you need to turn to through

• All other participants should contact the MSc Epidemiology Office instead, through

In short, as of now, it is no longer possible to skip the first exam option and -automatically- enroll in the second (re-sit) exam. Unauthorized absence during the first exam period results in no longer being able to finish the course that college year.

Requirements & material

To enroll in this course, you first need to follow these courses:


Compulsory study materials:

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